Atazanavir plasma concentrations may be reduced, decreasing the
Cl of benzodiazepines may be decreased.
Plasma levels may be increased by omeprazole, increasing the
therapeutic effects and adverse reactions.
Omeprazole and clarithromycin plasma concentrations may be
Drugs depending on gastric pH for bioavailability (eg,
ampicillin, cyanocobalamin, digoxin, ketoconazole, indinavir,
Absorption of these drugs may be affected.
Decreased plasma Cl and increased phenytoin t ½ .
St. John's wort
Omeprazole plasma levels may be reduced, decreasing the
Increased INR and PT, which may lead to abnormal bleeding and
increase the risk of death.